How Imatinib (Gleevec) Transformed Leukemia Treatment and Cancer Research https://www.genuinedrugs123.com/Blog-129-How-Imatinib-Gleevec-Transformed-Leukemia-Treatment-and-Cancer-Research.aspx Although a very few of the researchers who believed that generic mutations can cause Cancer were limited to lack of evidence to prove their hypothesis. During that time the patients suffering from the chronic myelogenous leukaemia were basically handed a death sentence because there wasn't any effective treatment available. So, Dr. Nowell, a researcher at University of Pennsylvania, spent all of his days peering into microscope analysing cancer cells taken from chronic myelogenous leukemia patients.