Poxet 60 mg should not be taken by individuals who are allergic to dapoxetine or any of the other ingredients in the medication. It should also be used with caution in individuals with certain medical conditions such as liver or kidney impairment, heart disease, or a history of psychiatric disorders. Poxet 60 mg should not be taken concurrently with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), or serotonin-norepinephrine reuptake inhibitors (SNRIs), due to the risk of serotonin syndrome. https://www.genericday.com/poxet-60-mg.html